March 17, 2006 Meeting
Public Affairs Lecture
Harinder Singh Prof. Harinder Singh

Howard Hughes Medical Institute Fellow and Louis Block Professor, Department of Molecular Genetics and Cell Biology, The University of Chicago

"The Scientific and Ethical Landscape of Stem Cell Biology"

Date:  March 17, 2006
Location:    Café La Cave
2777 Manheim Road
Des Plaines, IL 60018

Cost:  $32.00 for members of ACS and their guests, $34.00 for non-members,
     $16 for students or unemployed

Dinner reservations are required and should be received in the Section Office via phone (847-647-8405), fax (847-647-8364), email (, or web by noon on Tuesday, March 14.   PLEASE HONOR YOUR RESERVATIONS.  The Section must pay for all dinner orders.  No-shows will be billed.


5:00 -6:00 PM Topical Group
5:00 - 6:30  PM Job Club
5:30 - 6:00  PM Social Hour
6:30  PM Dinner - Early start time
7:30  PM Program  - Early start time

Topic: "The Scientific and Ethical Landscape of Stem Cell Biology"

Dr. Harinder Singh, Howard Hughes Medical Institute Fellow and Louis Block Professor, Department of Molecular Genetics and Cell Biology, The University of Chicago

Abstract:  Stem cell biology and regenerative medicine have recently emerged as exciting scientific and biomedical frontiers. Research in these areas has also raised significant ethical and public policy issues. The talk will cover scientific advances, promising lines of investigation and a rational framework for research support in this nascent field.

Biography:  Dr. Singh is a Howard Hughes Medical Institute (HHMI)  Fellow and Louis Block Professor in the Department of Molecular Genetics and Cell Biology (MG&CB) at the University of Chicago.  He received the degrees of M.Sc./B.Sc. with honors in biochemistry in the college of basic sciences and humanities of Punjab Agricultural University, Ludiana, Punjab, India in 1979, followed by a Ph.D. in biochemistry, molecular biology and cell biology at Northwestern University in 1984.  From 1984-1988, he was a Jane Coffin Childs Memorial Fellow for Medical Research at MIT.

Following his postdoctoral Fellowship, he joined the faculty at University of Chicago as an assistant professor in the Department of MG&CB and assistant HHMI investigator.  Prof. Singh has conducted research and published many papers in the fields of MG&CB and related areas.  He has 39 publications in peer-reviewed journals, as well as numerous review articles and book chapters..

Topical Group Meeting (5:00 PM)

Dr. Irini Zanze
Research Investigator, Medicinal Chemistry Technologies Group, Abbott Laboratories

"Targeted Libraries--The Design and Synthesis of Novel, Potent and Selective Kinase Inhibitors"

Abstract:   In recent years large diversity libraries have been replaced by more focused collections of compounds designed towards specific families of targets.  At Abbott we have initiated an effort to enhance the company's collection with kinase inhibitors.  This multi-disciplinary collaborative effort encompasses the areas of HTS, virtual screening, NMR-based screening, x-ray crystallography, molecular modeling, high throughput organic synthesis and scaffold oriented synthesis.  The presentation will describe the various approaches we have taken, with an emphasis on novelty and IP status, to produce collections of compounds that exhibit much higher hit rate against kinase targets than random collections.

Biography:   Irini Zanze received her Ph.D. with Professor Nicos Petasis at the University of Southern California, in 1994.  Upon completion of a short post-doc assignment with Professor Petasis, she joined Professor Koji Nakanishi's group at Columbia University for post-doctoral studies.  In 1997 she joined the Medicinal Chemistry Technologies Group at Abbott Laboratories where she is currently a research investigator.  Irini worked extensively on parallel synthesis and medicinal chemistry projects and on implementation of new technologies to pharmaceutical discovery.  Currently, she is responsible for the Scaffold Oriented Synthesis group, which focuses on enhancing the Abbott compound collection with proprietary diverse and /or targeted scaffolds and libraries.

Map and Directions

Parking:   Free


Updated 2/2/06